As the world-ending threat that LL&L have been preparing Deadpool to fight looms, Wade struggles with a crisis of conscience. Can he really be the Mithras, prophesied to save the world? Not to worry, LL&L has a possible replacement all lined up: Captain America! The aftermath of this cosmic conflict leaves Deadpool more unstable than usual — but when a familiar woman from his past returns, everything Wade Wilson knows about himself will be called into question! Now he must brace for revelations, recriminations and a very personal final battle against his worst enemy, T-Ray! Plus: Therapy sessions with Dr. Bong! And Deadpool crosses swords with Batroc, Bullseye, Wolverine, the pint-sized assassin Widdle Wade — and the lamest dead people in the Marvel Universe!